This white paper from SK pharmteco explores the development of a robust, GMP-compliant assay for detecting replication competent Adeno-Associated Virus (rcAAV) during commercial manufacturing. It details the challenges of rcAAV detection, innovative assay methodologies, and strategies to mitigate rcAAV formation, ensuring safety and regulatory compliance in gene therapy vector production. Download to gain insights into how advanced analytical techniques and optimized workflows support reliable and scalable AAV manufacturing.