Chromatography Services
Achieve high-purity APIs with chromatography services designed for complex separations. From batch to continuous chromatography through simulated moving bed (SMB) technology, we deliver efficient, scalable services across the product lifecycle from lab to commercial scale.
Chromatography Capabilities
Flexibility & Scalability
Chromatography solutions with batch and continuous (SMB) chromatography under CGMP, offering flexibility and scalability to deliver high-purity APIs throughout the product lifecycle. Our batch chromatography columns range from 4.6 mm to 800 mm, while our SMB units span from 8 × 10 mm up to 5 × 1,000 mm, to support your needs from lab to commercial production.
Expertise & Optimized Workflows
With over 30 years of experience in chromatography, we deliver scale-up protocols validated by 4 FDA/EMA-registered APIs using SMB technology, more than 50 developed processes, and multiple APIs successfully validated at commercial scale.
Sustainable Processes
Through our solvent recovery strategies, we enable greener chromatography with Process Mass Intensity values below 2 and 99.9% solvent recovery, delivering sustainable, cost-efficient API production.
Chromatography Solutions FAQs
SK pharmteco provides chromatography solutions across batch chromatography, continuous chromatography, and simulated moving bed chromatography to deliver high-purity APIs at every scale across the product lifecycle.
Simulated moving bed chromatography enables continuous separations with higher efficiency, reduced solvent consumption, and lower process mass intensity. SK pharmteco operates seven SMB units in the United States with a track record of FDA and EMA registered products.
Batch chromatography is available for reverse or normal phase separations with low- and high-pressure columns ranging from 4.6 millimeters to 800 millimeters. A batch chromatography process was recently validated at 800 millimeter scale in the United States.
Yes, Our chromatography services include more than 50 developed processes, multiple APIs validated at commercial scale, and four FDA and EMA registered products using simulated moving bed chromatography.
The team combines decades of chiral separation experience with dedicated R&D chemists, production engineers, and around-the-clock operational staff to ensure reliable chromatography services.
Our chromatography services include solvent recovery and reuse strategies that achieve process mass intensity values below two and recycle up to 99.9 percent of solvents, reducing waste and cost.
Chromatography solutions support complex separations including chiral molecules, diastereomers, regioisomers, and APIs with genotoxic or difficult impurities.
With more than three decades of experience, over 50 validated processes, and the largest simulated moving bed chromatography unit in North America, SK pharmteco delivers chromatography solutions that meet regulatory, scalability, and quality requirements.
Yes, Our chromatography solutions are available from grams to multi-ton scale, supporting clinical trial supply and validated commercial API manufacturing.
Our chromatography services are delivered from United States facilities with seven simulated moving bed chromatography units located onsite, providing flexible capacity and regulatory-ready infrastructure.
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