Catalyst Design

Catalyst design involves developing pharmaceutical catalysts tailored for specific reaction pathways to improve selectivity, yield, and impurity control. At SK pharmteco, in-house catalyst design supports both CGMP catalyst manufacturing and scalable continuous flow hydrogenation processes.

Continuous flow hydrogenation enables precise control of reaction conditions such as temperature, hydrogen flow, and pressure. This technology provides more predictable catalytic conversions, enhances process safety, and ensures consistent performance during small molecule synthesis at commercial scale.

SK pharmteco’s catalytic process development covers hydrogenation, oxidation, coupling, de-protection, and selective reduction reactions. Each is optimized through fixed bed reactors and flow chemistry systems designed for high reproducibility and controlled scalability.

All catalyst manufacturing and process optimization activities are conducted under CGMP conditions, ensuring traceability from raw materials to final product. Continuous monitoring and validated workflows guarantee regulatory compliance and reproducible results across production scales.

Fixed bed reactors allow for continuous operation with stable temperature profiles and efficient gas-liquid contact, extending catalyst lifespan and maintaining consistent reaction kinetics. These systems are central to SK pharmteco’s flow chemistry CDMO capabilities.

Our flow hydrogenation reactor systems can operate under high pressures (up to 300 bar) and high temperatures (up to 600 °C). This enables safe execution of challenging catalytic reactions, including those involving hydrogen, oxygen, or other reactive gases.

Through catalyst process optimization and continuous flow operation, SK pharmteco achieves high-yield reactions, longer catalyst lifetimes, and lower raw material consumption—reducing energy costs while maintaining quality and sustainability targets.

SK pharmteco’s process safety in catalysis includes closed-system flow reactors, automated pressure control, and real-time monitoring. These safeguards enable safe, stable continuous hydrogenation and other catalytic operations even under extreme process conditions.